Treating Alzheimer's Dementia With CT-Induced Low-Dose Ionizing Radiation: Problematic, Yet Potential for More Precise Inquiry

نویسندگان

  • Stephanie Raynor
  • James Giordano
چکیده

This commentary evaluates a recent single-case study by Cuttler et al that posits that a series of computerized tomographic (CT) scans ameliorated symptoms and signs of advanced Alzheimer's dementia in an elderly female patient. The report proposes that CT scanning delivered low-dose ionizing radiation (LDIR) that activated adaptive mechanisms in the brain to induce the effects observed and reported. However, the report evidenced methodologic problems that threaten the validity and value of its approach, stated results, and conclusions. We provide discussion of these issues, with view and intent toward developing more precise investigations of the potential mechanisms and utility of LDIR in treating Alzheimer's dementia and possibly other neurodegenerative disorders.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Response to Commentary: Treating Alzheimer Dementia With CT-Induced Low-Dose Ionizing Radiation: Problematic, Yet Potential for More Precise Inquiry

In their commentary, Raynor and Giordano make statements that ignore evidence and content of the case report. They refer to the therapy as a case study, misrepresenting the fact that it clearly describes a husband’s attempt to save the life of his 81-year-old wife. She was admitted to hospice on April 8, 2015, with advanced Alzheimer dementia (AD), with a life expectancy of less than 6 months. ...

متن کامل

Alzheimer ’s Disease: Possible Mechanisms Behind Neurohormesis Induced by Exposure to Low Doses of Ionizing Radiation

In 2016, scientists reported that human exposure to low doses of ionizing radiation (CT scans of the brain) might relieve symptoms of both Alzheimer’s disease (AD) and Parkinson disease (PD). The findings were unbelievable for those who were not familiar with neurohormesis. X-ray stimulation of the patient’s adaptive protection systems against neurodegenerative diseases was the mechanism pr...

متن کامل

Modulating effects of melatonin, vitamin C and saffron alone or in combination on radiation induced cell lethality; an in vitro study with Hela cells

Introduction: Radiation countermeasures are defined as use of an agent to minimize the deleterious effects of radiation therapy by administering the compound after the radiation exposure has occurred, regardless of toxicity. In spite of extensive study in this field, yet there is no suitable radioprotector introduced. In this study two naturally occurring antioxidants were stu...

متن کامل

Assessment of Patient Dose from CT Examinations in Khorasan, Iran

Introduction Computed Tomography scans are a very important tool for diagnosis and assessment of response to treatment in the practice of medicine. Ionizing radiation in medical imaging is undoubtedly one of the most powerful diagnostic tools in medicine. Yet, as with all medical interventions, there are potential risks in addition to the clear potential benefits. Materials and Methods Two refe...

متن کامل

Radiation hormesis and adoptive response induced by low doses of limiting radiation

  Ionizing radiation has long been known to produce detrimental biological effects. Although these harmful effects are the results of high doses of exposure, some other maladies such as mutation and cancer seems  to be induced at low doses of exposure. In recent decades, however, some pioneer scientists have indicated that ionizing radiation like many other essential agents has toxic effects  ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 15  شماره 

صفحات  -

تاریخ انتشار 2017